ONKOCET Ltd. has exhibited the devices from its portfolio on the MEDTEC UK exhibition in Birmingham, April 2011 through our partner Medical & Partners.
Scientists from the Sechenov Moscow Medical Academy, the Semenov Institute of Chemical Physics RAS and the Bauman Moscow State Technical University have shown that nitric oxide (NO), in addition to its other wonderful properties, promotes wound healing.
They performed research on laboratory rats. Under anaesthetic the creatures were administered regular wounds and then the scientists observed the way they healed. The experimenters had to obtain not only regular, but septic wounds too and therefore they infected half of the cases with staphylococcus.
For one minute wounded rats from the test groups were treated with nitric oxide on the second, third, fourth and sixth day after the operation. To do this the scientists used a special device, a “Plazon”, created at the Bauman MSTU. Thanks to high temperature a plasmochemical reaction occurs and NO is synthesized from oxygen and nitrogen, which cools to room temperature on output. The concentration of the derived nitric oxide can be regulated. The animals from the control groups were left unaffected.
It transpired that the wounds treated with nitric oxide healed much faster than those that were not. This applied both to dry and to septic wounds. Uninfected wounds in the control group healed on average in 29 days; after treatment with nitric oxide they healed in 22, a whole week being won. Septic wounds in the control group heal in thirty-three and a half days and after nitric oxide treatment –in twenty-four, nine days faster.
The scientists believe that nitric oxide treatment could become a promising method in wound treatment. As far as the Plazon device is concerned, its first clinical tests are underway. First results are encouraging.